MS cluster over VM using MSiscsi initiator

Dear Team,

We want ot create a cluster of two VMs using 2008 R2 on a vmware cluster. the IP subnet used to connect our SAN and ESX is 192.168.x.x and that of our LAN and VMs is 10.x.x.x.

So how can we add the RDMs to our VM using the MS iscsi initiator having two different IP subnets.

Is there any documentation available for the same? If not please help me to get this done.

Is there any performance issues using MS isci for cluster configuration ?

thanks